[Dave2]

There is nothing wrong with building a bike from "scratch"...provided you have enough experience to put together a component group that will work well together...or want to engage in the expensive lesson of trial and error.

If you are asking advice on a bicycle build from a bunch of guys on a car forum then I would suspect that you have little experience with component selection and integration. If this is the case I would recommend you go to a reputable bicycle shop, have a candid conversation with a sales rep regarding your needs and desires, and buy a complete bike. The bike manufacturers put together packages known to work well.
Once you gain some experience and get some exposure to the products on the market you can build a bike that will be satisfying to build and to ride.

I do need to put in a plug for my favorite...DeRosa.